Division Five leaders Queensfield recorded what could be a crucial 2-1 victory over nearest rivals Sun Inn Coate to open up a six-point lead.
Neil Robinson and Dave Smith netted for the leaders with Wayne Palmer replying for the Sun.
Jovial Monk retained third spot after their 4-2 win over Nationwide Life with a hat-trick for Dwayne Quinn and one for Tim Norris.
Lava Lounge slipped to a 2-1 home defeat to Wincanton with Tony Sardo and Joe O'Rourke finding the target for the victors.
Jason Lyne and a double from Ashley Oxborough gave ISSC a 3-2 home win over Brook House Farm.
In the top league, Juventus became the new leaders after their 6-3 win at AFC Gas, although they were made to work hard after trailing 3-1. They eventually triumphed with goals for Martin Crossman, Vinny Parker with a double and a Ricky Mazzotta hat-trick.
New Century WMC were held to a 4-4 draw by bottom team Tran Staff. Steve Shaw, Ryan Lovegrove, Mark Webb and Eddie Gordon scored for Century. In the other game Moonrakers won 4-2 at Wroughton WMC.
In Division Two, Blyskawica secured at least a runners-up spot after their latest win, 2-0 at Innogy Holdings. Once again it was those prolific scorers Ben Hollick and Chris Kyle with the spoils.
Jesters outgunned Alanbrooke 3-1 to mount their challenge with goals from Nod O'Dwyer, Robbie Quick and Steve Crame.
Two goals for Jason Edwards was all Swindon West Indians had to show in their surprise 6-2 home defeat by Innogy.
Thamesdown Nalgo closed in on joint leaders of Division Three Penhill United and South Marston after their 4-1 win at Coleview Sports. James Lewis grabbed Coleview's consolation goal.
Fox & Hounds and Nationwide shared four goals with Danny Bourne and Brian Murdoch on target for the Fox.
There were away wins for Compton Welding 4-0 at bottom club High St Club and Haydon Wick WMC who stormed to a 6-0 win at Wanborough.
In Division Four, Auto Colour won 3-0 at second-placed Motorola, and Highworth Swindon Fencing won 3-0 at Suffolk Arms which meant they swapped places in the league table.
A Mike Phelps hat-trick and a single strike from Gary Seward gave Windmill a 4-2 win at Lamb, for whom Tom Payne scored both. Red Lion proved too strong for Campbell James, winning 4-0 with a Rob Staynings four-timer.
In Division Six, Mark Emerson knocked in the Dolphin consolation in their surprise 5-1 home defeat by Ladsio.
Castrol GTX and G & F Bricklaying took full advantage of Dolphin's misfortune and returned to the top by recording victories. A Stuart Phillips double and Paul Stoddart gave Castrol a 3-0 home win over Swindon Cerney.
G & F won 5-1 at Halcrow for whom Brett Reay scored. A Billy Hunt double gave Philip Andrews a revenge win over Penetrators, who had beat them by the same scoreline the previous week.
H & H Athletic defeated Kingsdown United 4-2 thanks to goals from Ben Dalton, Matt Webster and a Barry Armstrong double. The Kingsdown scorers were Martin Lewis and Pete Nicholls.
Duckhams Q increased their lead at the top of Division Seven after winning 7-2 at Chesters. Stuart Carter (3), James Bradfield, John L'Estrange, Ian Rayner and Jon Cave-Ayland scored for the winners, and Morak Sheici scored both goals for Chesters.
WS One moved up a place after their 5-0 home win over Endeva. Vinny Price, Stuart Marriott, Ben Dickens and a double from Sam Brown did the business.
Intermach drew 2-2 with Dennis Removals with Mark Hillcoate and Gary Sawford on target. Andy Forbes and Matthew Hutchins replied for Dennis.
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